ColdFusion is super sweet; pretty much everything you want to do is incredibly obvious so there isn't much to say. Here are a few things I use quite often.

ColdFusion file upload

<!---Grab file from form values--->
<cfif IsDefined("FORM.file1")>
<cfset sFile1 = "#FORM.file1#">
<cfelse>
<cfset sFile1="">
</cfif>
<!---Upload said file to Server--->
<cffile action="upload"
filefield="file1"
destination="c:\your\destination"
nameconflict="Makeunique">

ColdFusion FTP

<!--- Open ftp connection --->
<cfftp connection="Myftp"
server="servername"
username="domain\username"
password="userPwd"
action="Open"
stoponerror="Yes">

<!--- Get the current directory name. --->
<cfftp connection=Myftp
action="GetCurrentDir"
stoponerror="Yes">

<!--- output directory name --->
<cfoutput>
The current directory is: #cfftp.ReturnValue#<br />
</cfoutput>

<!--- Get a listing of the directory. --->
<cfftp connection=Myftp
action="listdir"
directory="#cfftp.returnvalue#"
name="dirlist"
stoponerror="Yes">

<!--- Close the connection.--->
<cfftp action="close" connection="Myftp">
Did the connection close successfully?
<cfoutput>#cfftp.succeeded#</cfoutput><br />

<!--- output dirlist results --->
<hr>
<p>FTP <cfif sPath EQ ""> Directory<cfelse> File</cfif> Listing:</p>

<!---If there is no path show only directories--->
<cfif sPath EQ "">
<cftable query="dirlist" colheaders="yes" htmltable>
<cfif "#isdirectory#" EQ "yes">
<cfcol header="<B>Name</b>" TEXT="<a href='wherever.cfm'>#name#</a>">
<cfcol header="<B>LastModified</b>" TEXT="#DateFormat(lastmodified)#">
</cfif>
</cftable>
<cfelse>

<!---there is a path so show only files--->
<cftable query="dirlist" colheaders="yes" htmltable>
<cfif "#isdirectory#" EQ "no">
<cfcol header="<B>Name</b>" TEXT="<a href='wherever.cfm'>#name#</a>">
<cfcol header="<B>Path</b>" TEXT="#path#">
<cfcol header="<B>URL</b>" TEXT="#url#">
<cfcol header="<B>Length</b>" TEXT="#length#">
<cfcol header="<B>LastModified</b>" TEXT="#DateFormat(lastmodified)#">
<cfcol header="<B>IsDirectory</b>" TEXT="#isdirectory#">
</cfif>
</cftable>
</cfif>